Topics:

These topics are indicative, and new/innovative advances in biomechanics and computational simulation are welcome. Emphasise on validation techniques with input from life sciences and biological data are prioritised as are interdisciplinary links between medical technology, biosciences, computer science and the clinical community. An open invitation is also provided to those who wish to organise special sessions in a selected area of biomechanics. These special sessions will typically consist of six papers of 20 minutes duration each. If you wish to organise and chair a special session please contact the organisers.

  • Orthopaedics Systems, Implants and Medical Devices, Pre-Clinical Assessment Techniques
  • Computational Cell and Molecular Biomechanics, Cell and Extra-Cell-Matrix Interaction Mechanobiology, Tissue Adaptation, Fracture Healing and Transport Phenomena
  • Motion and Gait Analyses, Kinesiology, Patient-specific Musculoskeletal Modelling, Simulation-Based Methods for Calculating Musculoskeletal Forces, Integrating Modelling/Experiments to Study Clinical Problems (osteoarthritis, osteoporosis), Human Locomotion, Work Related Musculoskeletal Injuries and Sports Biomechanics
  • Dental Biomechanics, Implants, Craniofacial Reconstruction and Surgical Simulation, Orthodontics, Endodontics
  • Joint/Spine/Knee Biomechanics, Interveretebral Disc Models, Biomaterials, Muscle-ligament interaction and rehabilitation
  • The VPH project http://vph-noe.eu, Imaging and Visualization, Subject Specific Models, Simulation of Near Real-Time Reconstruction in 3-D, Imaging in Robotics, Virtual Surgery, Diagnostics and Organ Planning, Imaged Based Meshing for Structure Characteristics
  • Mechanobiology, Cytoskeletal Systems, Computational Biology, Medical and Bioinformatics
  • Theoretical Biomechanics, Soft Tissue Modelling and Constitutive Laws for Biological Structures Including Skin, Ligaments, Tendons, Muscles and Organs, Validation/Identification of Tissue Structures
  • Growth, Multiphysics/Multiscale Remodelling for Physiological Systems and Non-Deterministic Techniques
  • Biofluids and Fluid/Structure Interaction, CFD for Biodesign,  Modelling of Cardiovascular Access, Respiratory and Artificial/Hybrid Organs, Haemodynamics, Drug Release and Biomembranes
  • Cellular and Tissue Engineering/Regeneration, Scaffold Design, Computation of Porous Scaffold Properties and Scaffold Design to Simulate Material Degradation and Tissue Ingrowth, Multi-Level and Hierarchical Systems
  • Simulation in Ergonomics, Models for Hand, Grip and Finger Function, Footwear Biomechanics, Contact Modelling of the Skin-Object Interface
  • Neural IT, Modelling of Brain Function and Structure
  • Computer integrated surgery, computer generated haptics, multi-modal image registration and overlay systems for patient management

Mini-Symposium

The Integration of Medical Imaging with CAD/FEA/CFD/RP.
Chair: Panos Diamantopoulos. Sponsored by Materialise

During the last decade, computational techniques have found a profound role in biomechanics.
The use of medical imaging data in CAD/FEA/CFD and Rapid Manufacturing environments has been established, with many interesting applications. In the years to come, these techniques will be further developed and it is almost certain that will contribute to a major clinical tool. This scientific session, sponsored by Materialise, continues the success of the previously organised workshops in past CMBBE conferences.
The aim is to demonstrate and discuss current applications from the academic point of view, but also predict and present the technology of the future.

SPECIAL SESSIONS FORUM

Abstracts are invite for these special sessions which are chaired by experts from these fields. These areas are considered to be innovative, novel and of prime importance for the next generation of research and commercial development and to advance technology translation in healthcare.

SS1: Integrating Biology and Biomechanics: Soft and Hard Tissue Structures
Chairs: Brian Walker, Arup UK, Renato Natal Jorge, University of Porto, Portugal

SS2: Linking Imaging, Measurements, Modelling and Biology in Knee Biomechanics
Chairs: Debbie Mason and Cathy Holt, Cardiff University, UK

SS3: Spine and Interveretebral Disc Biomechanics
Chairs: Richard Hall, Leeds University, UK and Philippe K Zysset, TU of Vienna, Austria

SS4: Identification of Biomaterial Parameters using Inverse FE
Chairs: Sam L Evans, Cardiff University, UK and Stephane Avril, INSERM, France

SS5: The Virtual Physiological Human (VPH) project http://vph-noe.eu/ and Imaging in Biomechanics
Chairs: Marc Thiriet, France and Joao Tavares, University of Porto, Portugal

SS6: Patient-Specific Methods and Models in Cardiovascular Biomechanics and Pulmonary Biomechanics
Chair: Charley Taylor, Stanford University, USA and Pascal Verdonck, University of Ghent, Belgium

SS7: Computational Cell and Molecular Biomechanics, Cell and Extra-Cell-Matrix Interaction
Chair: Glen Niebur, University of Notre Dame, USA, Aleš Iglič, University of Ljubljana, Slovenia

SS8: Motion Analyses and Musculosketal Modelling
Chairs: Marcus Pandy, University of Melbourne and Cathy Holt, Cardiff University

SS9: Computational Modelling of the Brain, its Vasculature and Function
Chair: Tim David, University of Canterbury, Christchurch, New Zealand

SS10: Zimmer Special Session on Upper Limb Biomechanics
Chair:
Andrew Hopkins, Zimmer, Switzerland

SS11: Image-based Simulation for Biomechanics Applications
Chair:
Philippe Young, Simpleware Ltd.

SS1 Chairs: Brian Walker and Renato Natal Jorge

Integrating Biology and Biomechanics: Soft and Hard Tissue Structures
The session focuses on modeling biological structures concentrating on hard and soft tissues. Problems associated with defining of such structures including constitutive models, measurements of material properties and integrating biological processes are considered. Examples include simulation of muscle, skin, tendon and cartilage etc.

SS2 Chairs: Cathy Holt and Debbie Mason

Linking Imaging, Measurements, Modelling and Biology in Knee Biomechanics
Abnormal weight bearing on joints leads to diseases such as osteoarthritis whereas normal loading is essential to maintain a healthy skeleton. The forces associated with normal/abnormal loading and the way in which these forces influence joint function and pain are largely unknown. The modelling of mechanical loading patterns within normal/diseased human knees can inform clinical intervention and rehabilitation strategies and improve patient care. The linking of signalling events through specific mechanical stimuli can assist in future identifying mechanically regulated biomarkers of joint degeneration and associated therapeutic targets. This session focuses on advances in techniques which provide real world data and allow accurate patient specific models of the intact, diseased and prosthetic knee for correlation with biological studies. Topics include the imaging and measurement of knee anthropometrics including bone, cartilage and soft tissues; kinematics, contact stresses and dynamics and the mechanical loading associated with surgical intervention (HTO and TKR), and also with specific serum and synovial fluid biomarkers.

SS3 Chair: Richard Hall and Philippe K Zysset

Spine and Interveretebral Disc Biomechanics
This session will focus on vertebral augmentation, development of spinal devices and fixation systems, disc replacement and the biomechanics of the natural spine. Presentations will also be given by members of the EU funded Marie Curie Initial Training Network in spinal fracture ‘SpineFX’ which involves European partners from both the university and commercial sector. Here the mechanics of spinal fracture and enhancement techniques for treatments used to combat pain and disability will be considered. Presentations are also welcome in other innovative techniques in spine research.

SS4 Chairs: Sam L Evans and Stephane Avril

Identification of Biomaterial Parameters using Inverse FE
This session will focus on the problems of measuring the mechanical properties of biological materials using an inverse approach where the material properties in a model are adjusted to match experimental measurements.  Topics include experimental techniques, methods for rapid evaluation of models, optimisation algorithms and analysis of the uniqueness and uncertainty of the measured properties as well as complete studies.

SS5 Chairs: Marc Thiriet and Joao Tavares

The Virtual Physiological Human (VPH) project http://vphop.eu/ and Imaging in Biomechanics
This session will focus on patient-specific modeling and simulation of various body systems functioning in the framework of the Virtual Physiological Human (VPH) calls of EU FP7. Nowadays, multistage investigations aim at tackling time and length scales involved in the behaviour of biological systems (e.g., blood circulation, ventilation, digestion, renal purification, musculoskeletal apparatus, tumour growth, etc.) that sense, react, and adapt to environmental loadings. Topics include bio mathematical and biomechanical models as well as data mining for input parameters and experiments for validation. Structure segmentation, tracking, matching, alignment/registration, 3D reconstruction and motion and deformation analysis in medical imaging will be considered.

SS6 Chair: Charley Taylor and and Pascal Verdonck, University of Ghent, Belgium

Patient-Specific Methods and Models in Cardiovascular Biomechanics and Pulmonary Biomechanics
Functional biomedical imaging through computational fluid dynamics CFD and finite element analysis FEA provides a new technique to diagnose and treat cardiovascular and pulmonary pathology. Also medical device manufacturers and pharmaceutical industry benefit from this new approach to assess hydrodynamics, efficacy, performance of new devices and drugs in a virtual patient population. The session will focus on the state of the art developments in this innovative biomedical field.

SS7 Chair: Glen Niebur and Aleš Iglič

Computational Cell and Molecular Biomechanics, Cell and Extra-Cell-Matrix Interaction
Many cells are mechanosensitive, responding to stimuli such as stretching, shear stresses, bending and pressure. These signals have been used to stimulate tissue engineering constructs and to study cellular response to disease conditions. Computational modeling is providing a means to study these interactions in greater detail. The session will focus on techniques for constructing fluid and solid mechanics models of cell/matrix interactions, statistical mechanics models of cell membrane, multi-scale frame works for modeling from cell to tissue level, and applications to scientific hypotheses. Examples include: Microscale modeling of cells or the cytoskeleton, Models incorporating cell migration, cell shape transformation, formation of membrane micro- and nano-domains, budding of cell membrane, differentiation, or activation for tissue formation or degradation, Multiscale techniques and Modeling of tissue engineering or bioreactor constructs.

SS8 Chairs: Marcus Pandy and Cathy Holt

Motion Analyses and Musculosketal Modelling
This session will focus on the techniques and applications of motion analysis and musculoskeletal modelling. Kinematic, kinetic and dynamic models of human and animal locomotion provide valuable data and allow a greater understanding of the function of healthy and diseased joints and the dynamic control of motion. Measurement methods are challenging as they are prone to error and dynamic models require complex optimisation techniques. Topics include experimental techniques involving imaging, motion capture and EMG, optimisation and dynamic modelling and validation and application of such models to medical engineering problems such as implant design and surgical intervention, gait analysis and movement classification, orthotic and prosthetic application and animal locomotion.

SS9 Chair: Tim David

Computational Modelling of the Brain, its Vasculature and Function
This session will present reviewed papers on the computational modelling of the brain, it's function, blood supply , regulation and imaging. Submissions will be taken on areas of interest such as new numerical algorithms, imaging protocols, physiological simulation in cerebro-vasculature and other related areas.

SS10 Chair: Andrew Hopkins

Zimmer Special Session on Upper Limb Biomechanics
The upper limb presents unique challenges to health care providers, and is currently one of the fastest growing markets in orthopaedics. New and innovative prosthetic options for the shoulder, elbow, wrist and finger joints are emerging globally, and a sustained focus on the techniques used to analyse, describe and optimise the performance of these complicated joints is necessary to ensure their continued development. Submissions relating to the upper limb in the areas of FEA, kinematics, motion capture, prosthetic design, prosthetic performance, musculoskeletal anatomy and tribology are welcome.

SS11 Chair: Philippe Young

Image-based Simulation for Biomechanics Applications
This special session will look at issues surrounding 3D reconstruction from radiology images, and in using 3D image data to generate Rapid Prototyping, CAD, and Finite Element models. Papers are invited in which image-based techniques have been used for the generation of analysis models for any biomechanical applications. A frank discussion of both the opportunities and the challenges faced when modelling biomechanical systems using image data will be encouraged.